1259224-11-7

Basic information

• Product Name: 5-broMo-2,3-diphenyl-1H-indole
• Synonyms: 5-broMo-2,3-diphenyl-1H-indole;5-Bromo-2,3-diphenylindole
• CAS NO: 1259224-11-7
• Molecular Formula: C20H14BrN
• Molecular Weight: 348.23586
• Mol File: 1259224-11-7.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 494.3±33.0 °C(Predicted)
• Appearance: /
• Density: 1.400
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 15.58±0.30(Predicted)
• CAS DataBase Reference: 5-broMo-2,3-diphenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-broMo-2,3-diphenyl-1H-indole(1259224-11-7)
• EPA Substance Registry System: 5-broMo-2,3-diphenyl-1H-indole(1259224-11-7)

Safety Data

• Hazardous Substances Data: 1259224-11-7(Hazardous Substances Data)

Usage

Description

5-Bromo-2,3-diphenyl-1H-indole is a chemical compound belonging to the indole family, with the molecular formula C20H14BrN. It is a brominated derivative characterized by the presence of a bromine atom at the 5-position and two phenyl groups at the 2and 3-positions. This unique structure endows it with intriguing biological properties, making it a promising candidate for various applications in medicinal chemistry.

Uses

Used in Medicinal Chemistry:
5-Bromo-2,3-diphenyl-1H-indole is used as a building block for the synthesis of complex organic molecules due to its unique structure and potential biological activities.
Used in Anticancer Applications:
In the pharmaceutical industry, 5-bromo-2,3-diphenyl-1H-indole is used as an anticancer agent for its potential to exhibit biological properties that can combat cancer cells.
Used in Antimicrobial Applications:
5-Bromo-2,3-diphenyl-1H-indole is utilized as an antimicrobial agent in the field of medicine, leveraging its ability to exhibit properties effective against various microorganisms.
Used in Pharmaceutical Drug Development:
Due to its interesting biological properties and unique structure, 5-bromo-2,3-diphenyl-1H-indole serves as an attractive target for further studies and development of new pharmaceutical drugs in the medical and pharmaceutical industries.

Upstream product

• 586-78-7 para-nitrophenyl bromide 

Relevant articles and documents

Rhodium(III)-Catalyzed Redox-Neutral C-H Annulation of Arylnitrones and Alkynes for the Synthesis of Indole Derivatives

By using a nitrone as the oxidizing directing group, a mild, practical and efficient rhodium(III)-catalyzed C-H functionalization for the synthesis of indole derivatives has been developed. This reaction obviates the need for an external oxidant and shows good functional group tolerance. The employment of a sterically hindered Mes group on the carbon center of the nitrone is crucial to produce indoles in high yield.

A palladium/carbon as catalyst preparation of indole compounds method (by machine translation)

The present invention provides a palladium/carbon as catalyst preparation of indole compounds method, aniline and its analogs in the palladium/carbon with the alkyne under the action of the catalytic cyclization reaction, to form the corresponding indoles. This method has the advantages of: simple preparation method, the raw material is cheap, high yield, without protection of inert gas, the reaction temperature is relatively mild. (by machine translation)

ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

PROBLEM TO BE SOLVED: To provide an indole-based compound excellent in hole injection, hole transport capability and light-emitting capability and to provide an organic electroluminescent element that includes the compound in an organic layer and is excellent in characteristics such as luminous efficiency, drive voltage, life and the like. SOLUTION: The indole-based compound is represented by the formula as given below and the organic electroluminescent element includes the compound in one or more organic layers. [R1 and R2 are each independently H, D, alkyl or the like; Y3 to Y8 are CR4; R4s are each independently H, D, alkyl, aryl or the like; Z1 to Z6 are each independently N or AR6; AR6A and B are each independently alkylcycloalkyl, aryl, heteroaryl or the like; p and q are each independently an integer of 0 to 3; r and s are each independently an integer of 0 to 5; and r+s≥1] SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT