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5-Bromo-2,3-diphenyl-1H-indole is a chemical compound belonging to the indole family, with the molecular formula C20H14BrN. It is a brominated derivative characterized by the presence of a bromine atom at the 5-position and two phenyl groups at the 2and 3-positions. This unique structure endows it with intriguing biological properties, making it a promising candidate for various applications in medicinal chemistry.

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  • 1259224-11-7 Structure
  • Basic information

    1. Product Name: 5-broMo-2,3-diphenyl-1H-indole
    2. Synonyms: 5-broMo-2,3-diphenyl-1H-indole;5-Bromo-2,3-diphenylindole
    3. CAS NO:1259224-11-7
    4. Molecular Formula: C20H14BrN
    5. Molecular Weight: 348.23586
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1259224-11-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 494.3±33.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.400
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 15.58±0.30(Predicted)
    10. CAS DataBase Reference: 5-broMo-2,3-diphenyl-1H-indole(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-broMo-2,3-diphenyl-1H-indole(1259224-11-7)
    12. EPA Substance Registry System: 5-broMo-2,3-diphenyl-1H-indole(1259224-11-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1259224-11-7(Hazardous Substances Data)

1259224-11-7 Usage

Uses

Used in Medicinal Chemistry:
5-Bromo-2,3-diphenyl-1H-indole is used as a building block for the synthesis of complex organic molecules due to its unique structure and potential biological activities.
Used in Anticancer Applications:
In the pharmaceutical industry, 5-bromo-2,3-diphenyl-1H-indole is used as an anticancer agent for its potential to exhibit biological properties that can combat cancer cells.
Used in Antimicrobial Applications:
5-Bromo-2,3-diphenyl-1H-indole is utilized as an antimicrobial agent in the field of medicine, leveraging its ability to exhibit properties effective against various microorganisms.
Used in Pharmaceutical Drug Development:
Due to its interesting biological properties and unique structure, 5-bromo-2,3-diphenyl-1H-indole serves as an attractive target for further studies and development of new pharmaceutical drugs in the medical and pharmaceutical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 1259224-11-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,2,2 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1259224-11:
(9*1)+(8*2)+(7*5)+(6*9)+(5*2)+(4*2)+(3*4)+(2*1)+(1*1)=147
147 % 10 = 7
So 1259224-11-7 is a valid CAS Registry Number.

1259224-11-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-2,3-diphenyl-1H-indole

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1259224-11-7 SDS

1259224-11-7Upstream product

1259224-11-7Downstream Products

1259224-11-7Relevant articles and documents

Rhodium(III)-Catalyzed Redox-Neutral C-H Annulation of Arylnitrones and Alkynes for the Synthesis of Indole Derivatives

Zhou, Zhi,Liu, Guixia,Chen, Yan,Lu, Xiyan

, p. 2944 - 2950 (2015)

By using a nitrone as the oxidizing directing group, a mild, practical and efficient rhodium(III)-catalyzed C-H functionalization for the synthesis of indole derivatives has been developed. This reaction obviates the need for an external oxidant and shows good functional group tolerance. The employment of a sterically hindered Mes group on the carbon center of the nitrone is crucial to produce indoles in high yield.

Method for preparing indole compounds by using rhodium/carbon as catalyst

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Paragraph 0029-0031; 0034; 0036, (2018/04/26)

The invention provides a method for preparing indole compounds by using rhodium/carbon as a catalyst. Corresponding indole compounds are formed through subjecting aniline and analogs thereof and alkyne to a catalytic cyclization reaction in the presence of the rhodium/carbon. The method has the beneficial effects that the preparation method is simple in process, the raw materials are cheap and readily available, the yield is high, inert-gas protection is not required, and the reaction temperature is relatively moderate.

A palladium/carbon as catalyst preparation of indole compounds method (by machine translation)

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Paragraph 0029; 0030; 0031; 0033, (2018/06/15)

The present invention provides a palladium/carbon as catalyst preparation of indole compounds method, aniline and its analogs in the palladium/carbon with the alkyne under the action of the catalytic cyclization reaction, to form the corresponding indoles. This method has the advantages of: simple preparation method, the raw material is cheap, high yield, without protection of inert gas, the reaction temperature is relatively mild. (by machine translation)

ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME

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Paragraph 0476; 0478; 0479; 0493-0496, (2018/08/30)

The present invention relates to an indole-based compound with excellent hole injection and hole transport ability; and to an organic electroluminescent device which includes the compound in one or more layers and thus has increased light emitting efficiency, needs lower driving voltages, and has an extended life span. According to the present invention, the electroluminescent device includes: (i) a positive electrode; (ii) a negative electrode; and (iii) one or more organic layers interposed between the positive electrode and the negative electrode.

ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

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Paragraph 0173; 0174; 0181; 0182, (2016/10/07)

PROBLEM TO BE SOLVED: To provide an indole-based compound excellent in hole injection, hole transport capability and light-emitting capability and to provide an organic electroluminescent element that includes the compound in an organic layer and is excellent in characteristics such as luminous efficiency, drive voltage, life and the like. SOLUTION: The indole-based compound is represented by the formula as given below and the organic electroluminescent element includes the compound in one or more organic layers. [R1 and R2 are each independently H, D, alkyl or the like; Y3 to Y8 are CR4; R4s are each independently H, D, alkyl, aryl or the like; Z1 to Z6 are each independently N or AR6; AR6A and B are each independently alkylcycloalkyl, aryl, heteroaryl or the like; p and q are each independently an integer of 0 to 3; r and s are each independently an integer of 0 to 5; and r+s≥1] SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT

NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME

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, (2015/09/22)

The present invention relates to a novel indole-based compound having excellent hole injection and transport capabilities, light-emitting capabilities, and the like, and an organic electroluminescence device which includes the indole-based compound in one or more organic material layers thereof so as to improve characteristics such as light-emitting efficiency, driving voltage, and lifespan.

ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

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Paragraph 0411; 0412; 0427-0430, (2016/10/07)

The present invention refers to hole injection and transporting ability, light emitting ability selected from the group consisting of triazole new organic compound and said at least one compound organic luminous efficiency by the inclusion of layer, driving voltage, longevity, etc. are formed on the relates to organic electroluminescence device.

This is a novel compound and an organic electroluminescence element including

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Paragraph 0109; 0114, (2016/10/07)

The present invention relates to a novel indole-based compound having excellent hole injection and transport capabilities, light-emitting capabilities, and the like, and an organic electroluminescence device which includes the indole-based compound in one or more organic material layers thereof so as to improve characteristics such as light-emitting efficiency, driving voltage, and lifespan.

ORGANIC COMPOUNDS AND ORGANIC ELECTRO LUMINESCENCE DEVICE COMPRISING THE SAME

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Paragraph 0231; 0232; 0233; 0248-0250, (2016/10/08)

The present invention relates to organic compounds and an organic electroluminescent device comprising the same. According to the present invention, the organic compounds can improve light emitting efficiency, driving voltage, lifespan, etc. of the organic electroluminescent device by being used in an organic layer, desirably a light emitting layer of the organic electroluminescent device. The compounds are represented by chemical formula 1.COPYRIGHT KIPO 2015

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