125949-72-6

Basic information

• Product Name: diphenylmethyl (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• CAS NO: 125949-72-6
• Molecular Formula: C₂₃H₂₂N₄O₃S
• Molecular Weight: 434.5108
• Mol File: 125949-72-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 634.1°C at 760 mmHg
• Flash Point: 337.3°C
• Density: 1.39g/cm³
• Vapor Pressure: 5.53E-16mmHg at 25°C
• Refractive Index: 1.706
• CAS DataBase Reference: diphenylmethyl (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diphenylmethyl (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(125949-72-6)
• EPA Substance Registry System: diphenylmethyl (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate(125949-72-6)

Safety Data

• Hazardous Substances Data: 125949-72-6(Hazardous Substances Data)

Upstream product

• 85573-73-5 2β-chloromethyl-2α-methylpenicillin-3α-carboxylic acid diphenylmethyl ester 
• 288-36-8 1,2,3-triazole 
• 80353-26-0 6α-bromopenicillan-3α-carboxylic acid diphenylmethyl ester-1β-oxide 
• 87579-78-0 diphenylmethyl (2S,5R,6R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4-oxide 
• 205320-23-6 benzhydryl-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-4-oxide 
• 74189-25-6 diphenylmethyl 6α-bromopenicillanate 
• 551-16-6 6-Aminopenicillanic Acid 
• 24138-28-1 6-bromopenicillanic acid 
• 85573-72-4 (R)-2-[2-(benzothiazol-2-yldisulfanyl)-4-oxo-azetidin-1-yl]-3-methyl-butyl-3-enoic acid benzhydryl ester 

Downstream Products

• 89786-04-9 tazobactam 

Relevant articles and documents

Preparation method of tazobactam diphenylmethyl ester intermediate

The invention provides a preparation method of a tazobactam diphenylmethyl ester intermediate. The preparation method comprises following steps: 1H-1, 2, 3-triazole is reacted with DBU so as to obtaina reacted solution of 1, 2, 3-triazole and DBU salt, a

PENAM CRYSTAL AND PROCESS FOR PRODUCING THE SAME

The present invention provides novel 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3α-carboxylic acid benzhydryl ester (TMPB)-acetone crystals for use in the production of 2α-methyl-2β-[(1,2,3-triazol-1-yl)methyl]penam-3α-carboxylic acid 1,1-dioxide benz

Process for preparation of penam derivatives from cepham derivatives

The present invention relates to a process for preparing 2α-methyl-2β-substituted methyl penam derivatives from cepham derivatives, more particularly the present invention provides a novel process for preparing 2β-heterocyclyl methyl penam derivatives of the formula (I) wherein R1 represents carboxylic acid protecting group; R2 and R3 may be same or different and independently represent hydrogen, halogen, NH2, acylamino, phthalimido with a proviso that both R2 and R3 are not NH2, acylamino, phthalimido; Het represents a 5 or 6 membered nitrogen containing heterocycle ring system having one or more heteroatoms selected from O, S, or N.