1259490-12-4Relevant academic research and scientific papers
4,5-Dihydroxyimidazolidin-2-ones in α-ureidoalkylation of N-carboxyalkyl-, N-hydroxyalkyl-, and N-(aminoalkyl)ureas 4.* α-Ureidoalkylation of N-(2-acetylaminoethyl)ureas
Gazieva,Lozhkin,Baranov,Kravchenko,Makhova
, p. 642 - 646 (2010)
α-Ureidoalkylation of N-(2-acetylaminoethyl)ureas with various 4,5-dihydroxyimidazoli- din-2-ones was systematically studied. Novel N-(2-acetylaminoethyl)glycolurils were obtained. Their yields were found to decrease both when moving from 1,3-H2- to 1,3-Alk2-4,5- dihydroxy- imidazolidin-2-ones and when increasing the size of the substituent at the second N atom in the starting acetylaminoethylurea. The higher yields were achieved with 4,5-diphenyl-4,5- dihydroxyimidazolidin-2-one as the starting compound. 2-(2-Acetylaminoethyl)-4-methylgly- coluril exhibits nootropic activity.
