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2-(1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-3-phenyl-4-quinolinecarbonitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1259521-75-9

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1259521-75-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1259521-75-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,5,2 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1259521-75:
(9*1)+(8*2)+(7*5)+(6*9)+(5*5)+(4*2)+(3*1)+(2*7)+(1*5)=169
169 % 10 = 9
So 1259521-75-9 is a valid CAS Registry Number.

1259521-75-9Downstream Products

1259521-75-9Relevant academic research and scientific papers

Synthesis and SAR study of potent and selective PI3Kδ inhibitors

Bui, Minna,Hao, Xiaolin,Shin, Youngsook,Cardozo, Mario,He, Xiao,Henne, Kirk,Suchomel, Julia,McCarter, John,McGee, Lawrence R.,San Miguel, Tisha,Medina, Julio C.,Mohn, Deanna,Tran, Thuy,Wannberg, Sharon,Wong, Jamie,Wong, Simon,Zalameda, Leeanne,Metz, Daniela,Cushing, Timothy D.

, p. 1104 - 1109 (2015/02/19)

2,3,4-Substituted quinolines such as (10a) were found to be potent inhibitors of PI3Kδ in both biochemical and cellular assays with good selectivity over three other class I PI3K isoforms. Some of those analogs showed favorable pharmacokinetic properties.

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