1259529-47-9Relevant academic research and scientific papers
Enantioselective synthesis of a key A-ring intermediate for the preparation of 1α,25-dihydroxyvitamin D3
Chen, Yan,Ju, Tong
supporting information; experimental part, p. 86 - 89 (2011/04/12)
A novel approach to the key A-ring α, β-unsaturated aldehyde 1, an important intermediate for the preparation of 1α,25-dihydroxyvitamin D3, has been developed. The strategy started from the inexpensive starting material (R)-carvone with an ene reaction serving as the key step toward the potential synthesis of vitamin D3 analogues bearing the modification at the C-2 position.
