1259576-91-4 Usage
Uses
Used in Pharmaceutical Research and Development:
(2-bromo-1H-indol-1-yl)(phenyl)methanone serves as a key intermediate in the synthesis of various pharmaceutical agents. Its unique structure, which includes the indole ring and the bromo and phenyl substituents, contributes to its potential as a precursor for developing new drugs with enhanced biological activities.
Used in Medicinal Chemistry:
As an indole derivative, (2-bromo-1H-indol-1-yl)(phenyl)methanone is employed in medicinal chemistry for its diverse biological properties. (2-bromo-1H-indol-1-yl)(phenyl)methanone's antitumor, antimicrobial, and anti-inflammatory activities make it a promising candidate for the development of therapeutic agents targeting a range of diseases and conditions.
Used in Chemical Synthesis:
The presence of the bromo group in (2-bromo-1H-indol-1-yl)(phenyl)methanone makes it a versatile building block for further chemical synthesis. It can undergo functionalization reactions to generate a variety of novel compounds with potentially improved or modified biological activities, expanding its utility in the creation of new pharmaceuticals and chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 1259576-91-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,5,7 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1259576-91:
(9*1)+(8*2)+(7*5)+(6*9)+(5*5)+(4*7)+(3*6)+(2*9)+(1*1)=204
204 % 10 = 4
So 1259576-91-4 is a valid CAS Registry Number.
1259576-91-4Relevant academic research and scientific papers
Synthesis of 6H-isoindolo[2,1-a]indol-6-ones through a sequential copper-catalyzed C-N coupling and palladium-catalyzed C-H activation reaction
He, Hua-Feng,Dong, Sheng,Chen, Yi,Yang, Yang,Le, Yueqin,Bao, Weiliang
scheme or table, p. 3112 - 3116 (2012/06/01)
A series of 6H-isoindolo[2,1-a]indol-6-ones were synthesized through one-pot sequential coupling reactions, which were comprised of a copper-catalyzed C-N coupling cyclization and a palladium-catalyzed C-H activation course. General chemicals benzoyl chlorides and o-gem-dibromovinyl anilines were employed as the starting substrates.
Facile synthesis of 2-bromoindoles by ligand-free CuI-catalyzed intramolecular cross-coupling of gem-dibromoolefins
Jiang, Baishan,Tao, Kemei,Shen, Wang,Zhang, Jiancun
experimental part, p. 6342 - 6344 (2011/01/04)
A mild and efficient synthesis of 2-bromoindoles by ligand-free CuI-catalyzed intramolecular cross-coupling of gem-dibromoolefins was developed. Reactions were carried out in toluene at room temperature and the corresponding 2-bromoindoles were obtained in excellent yields.
