125997-14-0

Usage

Uses

Used in Medicinal Chemistry:
1-(3-fluorophenyl)-4-penten-1-ol is used as a compound in medicinal chemistry for its potential applications in the development of pharmaceuticals. The presence of a fluorine atom in the structure often leads to enhanced properties in drug candidates, making 1-(3-fluorophenyl)-4-penten-1-ol a promising candidate for further study and development.
Used in Synthetic Chemistry:
1-(3-fluorophenyl)-4-penten-1-ol is used as a building block in synthetic chemistry for the production of other chemical compounds or materials. The penten-1-ol moiety in its structure indicates its potential for use in creating a variety of synthesized products, which may have applications in various industries.
Used in Pharmaceutical Development:
1-(3-fluorophenyl)-4-penten-1-ol is used as a starting material or intermediate in the pharmaceutical industry for the synthesis of new drugs. The unique structure of 1-(3-fluorophenyl)-4-penten-1-ol, including the fluorine atom and the double bond, may provide specific advantages in the design and synthesis of novel pharmaceutical agents.
Used in Chemical Research:
1-(3-fluorophenyl)-4-penten-1-ol is used as a subject of study in chemical research to better understand its properties, reactivity, and potential applications. Further investigation into 1-(3-fluorophenyl)-4-penten-1-ol may reveal additional uses and benefits in various fields, including materials science, environmental chemistry, and more.

Upstream product

• 7103-09-5 4-but-1-enylmagnesium bromide 
• 456-48-4 3-Fluorobenzaldehyde 

Downstream Products

• 125997-07-1 C₁₂H₁₁⁽²⁾H₂F 
• 125997-01-5 1-(3-fluorophenyl)-4-penten-1-one 

Relevant academic research and scientific papers

Highly Enantioselective Construction of Dihydrooxazines via Pd-Catalyzed Asymmetric Carboetherification

A straightforward synthesis of highly enantioenriched 5,6-dihydro-4H-1,2-oxazines is realized by Pd-catalyzed asymmetric carboetherification of γ,δ-alkenyl oximes with (hetero)aryl and alkenyl halides in the presence of a commercially available bisphosphine ligand. The enantioenriched products can be facilely converted to functionalized alcohols with high fidelity of chiral transfer.

Copper-Catalyzed Cope-Type Hydroamination of Nonactivated Olefins toward Cyclic Nitrones: Scope, Mechanism, and Enantioselective Process Development

The catalytic synthesis of cyclic nitrones, an important type of functional molecules for both synthetic chemistry and related fields, remains underdeveloped. Herein we report the copper-catalyzed Cope-type hydroamination of oximes with pendant nonactivated olefins, which enables facile access to a series of five- and six-membered cyclic nitrones under mild conditions. In this study, heterocycle-tethered oximes were employed in the Cope-type hydroamination reaction for the first time. High enantioselectivity was achieved for carbon-tethered γ,δ-vinyl oximes to afford enantioenriched five-membered cyclic nitrones. The results of preliminary mechanistic studies indicate a mononuclear catalytic species and a unified catalytic pathway over a large temperature range.

Mechanism of the palladium dichloride catalyzed cope rearrangement of acyclic dienes. A substituent effect study

The PdCl2-catalyzed Cope rearrangement of eight 2-aryl-1,5-hexadienes was studied. No simple substituent effect relationship was found, since the catalyzed-rearrangement rate was decreased by introducing both electron-withdrawing and electron-d