1259986-76-9Relevant academic research and scientific papers
Synthesis of a tetrasaccharide related to the triterpenoid saponin isolated from Schima noronhae
Verma, Priya,Raj, Ritu,Roy, Bimalendu,Mukhopadhyay, Balaram
experimental part, p. 2413 - 2418 (2010/12/25)
A concise synthesis of a tetrasaccharide related to the cell-growth inhibitory triterpenoid saponin isolated from Schima noronhae is reported. A late stage 2,2,6,6-tetramethylpiperidinyloxy (TEMPO)-mediated oxidation of a primary hydroxyl group to carboxylic acid has been achieved under phase-transfer conditions. Stereoselective glycosylations were carried out using thioglycoside or glycosyl trichloroacetimidate activation using sulfuric acid immobilized on silica (H2SO4-silica) in conjunction with N-iodosuccinimide and alone, respectively.
