126-13-6

Basic information

• Product Name: SUCROSE ACETATE ISOBUTYRATE
• Synonyms: sucroseacetoisobutyrate;SUCROSE DIACETATE HEXAISOBUTYRATE;SAIB;SAIB-100;SAIB-SG;SUCROSE ACETATE ISOBUTYRATE, 90 WEIGHT %;SUCROSE ACETATE ISOBUTYRATE 90 WT. % SOL;Sucrosediacetateisobutyrate
• CAS NO: 126-13-6
• Molecular Formula: C40H62O19
• Molecular Weight: 846.91
• EINECS: 204-771-6
• Mol File: 126-13-6.mol
• Article Data: 0

Chemical Properties

• Melting Point: −83 °C
• Boiling Point: 78 °C
• Flash Point: 70 °F
• Appearance: clear colorless to slightly yellow viscous liquid
• Density: 1.146 g/mL at 25 °C
• Vapor Pressure: 40 mm Hg ( 20 °C)
• Refractive Index: n20/D 1.446
• CAS DataBase Reference: SUCROSE ACETATE ISOBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: SUCROSE ACETATE ISOBUTYRATE(126-13-6)
• EPA Substance Registry System: SUCROSE ACETATE ISOBUTYRATE(126-13-6)

Safety Data

• Hazard Codes: Xi,Xn,F
• Statements: 20/21/22-36/37/38-68/20/21/22-10-52/53-11
• Safety Statements: 16-26-36-61
• RIDADR: UN 1173 3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 126-13-6(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to slightly yellow viscous liquid

Uses

food additive, plasticizer

InChI:InChI=1/C18H30O13/c1-7(2)16(26)29-15-12(24)10(5-20)30-18(15,6-21)31-17-14(27-8(3)22)13(25)11(23)9(4-19)28-17/h7,9-15,17,19-21,23-25H,4-6H2,1-3H3/t9-,10-,11-,12-,13+,14-,15+,17-,18+/m1/s1

Related news

Research SectionStudies on the metabolism of SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) in the rat and in man09/28/2019

In vitro and in vivo studies in the rat and in man were conducted on the metabolic fate of sucrose acetate isobutyrate (SAIB). In vitro studies with rat tissues showed that SAIB was substantially hydrolysed by non-specific esterases associated with the intestinal mucosa; little hydrolysis occurr...detailed

ReviewMetabolism and pharmacokinetics of SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) (SAIB) and sucrose octaisobutyrate (SOIB) in rats, dogs, monkeys or humans: a review10/01/2019

Sucrose acetate isobutyrate (SAIB), a mixture of esters of sucrose with a composition approximating the name sucrose diacetate hexaisobutyrate, has been used for over 30 years in many countries as a ‘weighting’ or ‘density-adjusting’ agent in non-alcoholic carbonated and non-carbonated bever...detailed

Induction of mucosal and systemic antibody specific for SeMF3 of Streptococcus equi by intranasal vaccination using a SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) based delivery system09/27/2019

Streptococcus equi causes equine strangles, a highly contagious disease of the upper respiratory tract. The antiphagocytic surface protein SeM is strongly immunogenic and evokes mucosal and systemic antibodies during convalescence. The present study investigated the potential of sucrose acetate ...detailed

Research SectionLack of genotoxic effects of SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) (SAIB)09/26/2019

Sucrose acetate isobutyrate (SAIB) was tested for potential genotoxic activity in four different in vitro assay systems. Two independent trials of a Salmonella reverse mutation assay (using strains TA98, TA100, TA1535, TA1537 and TA1538) showed no increases in revertant frequencies at doses up t...detailed

Intracranial drug-delivery scaffolds: Biocompatibility evaluation of SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) gels09/25/2019

Introduction: Sucrose acetate isobutyrate (SAIB) is a water insoluble, biodegradable gel used for controlled-release oral and subcutaneous drug delivery. We investigated SAIB compatibility in the rat central nervous system (CNS) by implanting solutions of SAIB in adult and in neonatal brains. Me...detailed

Research ArticlePharmaceutics, Drug Delivery and Pharmaceutical TechnologyImprovement of the Antitumor Efficacy of Intratumoral Administration of Cucurbitacin Poly(Lactic-co-Glycolic Acid) Microspheres Incorporated in In Situ-Forming SUCROSE ACETATE ISOBUTYRATE (cas 126-13-6) Depots09/10/2019

Localized drug delivery strategies for cancer therapy have been introduced for decades as a means of increasing drug concentration at tumor target site and minimizing systemic toxicities. In this paper, a combination of microspheres (MSs) and sucrose acetate isobutyrate (SAIB) in situ-forming im...detailed