126002-52-6

Upstream product

• 1121-30-8 1-hydroxy-2(1H)-pyridinethione 
• 135967-09-8 4-phenyl-1-phenylsulfonyl-1-(pyridin-2-ylthio)-1-trimethylsilylbutane 
• 5535-48-8 PVS 
• 114050-31-6 3-Phenyl-propionic acid 2-thioxo-2H-pyridin-1-yl ester 

Downstream Products

• 92643-35-1 4-phenyl-1-phenylsulphonyl butane 
• 87837-53-4 (E)-[(4-phenylbut-1-en-1-yl)sulfonyl]benzene 
• 135967-04-3 4-phenyl-1-phenylsulfonyl-1-(pyridin-2-ylsulfinyl)butane 
• 87837-53-4 4-phenyl 1-phenylsulphonyl but-1-ene 
• 768-56-9 4-Phenylbut-1-ene 
• 135966-87-9 Trifluoro-acetic acid 1-benzenesulfonyl-4-phenyl-1-(pyridin-2-ylsulfanyl)-butyl ester 
• 1821-12-1 4-Phenylbutyric acid 

Relevant academic research and scientific papers

The Invention of Radical Reactions. XXXIII Homologation Reactions of Carboxylic Acids by Radical Chain Chemistry

Various carbon radicals can be generated from carboxylic acids via the corresponding Barton esters.These radicals can be used for the synthesis of longer chain homologues of the original acids.

HOMOLOGATION OF ACIDS via CARBON RADICALS GENERATED FROM THE ACYL DERIVATIVES OF N-HYDROXY-2-THIOPYRIDONE. (THE TWO-CARBON PROBLEM).

Reaction of suitable substituted olefins with carbon radicals generated from the acyl derivatives of N-hydroxy-2-thiopyridone results in the formation of precursors for the corresponding homo-acids.These compounds can then be transformed to the desired end-products in high yield under mild conditions.

Decarboxylative radical addition to vinylsulphones and vinylphosphonium bromide: Some further novel transformations of geminal (pyridine-2-thiyl) phenylsulphones

Irradiation of O-acyl derivatives 1 of N-hydroxy-2-thiopyridone with visible light in the presence of phenyl vinyl sulphone or vinyl triphenylphosphonium bromide leads to the corresponding adducts 8 and 9 which can undergo a wide variety of further transformations.

THE ROLE OF ORGANIC TELLURIDES AS ACCUMULATORS AND EXCHANGERS OF CARBON RADICALS

Primary carbon radicals, generated by photolysis of acyl derivatives of N-hydroxy-2-thiopyridone, exchange efficiently on diisopropyl telluride to give isopropyl radicals which can in turn be trapped by radicophilic olefins.