1260020-46-9Relevant academic research and scientific papers
MEXILETINE PRODRUGS
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Page/Page column 59; 60, (2012/07/13)
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) pharmaceutical compositions containing such prodrugs. Methods for treating myotonic conditions, while reducing the inherent adverse G1 side effects associated with mexiletine, increasing the bioavailability of mexiletine, and improving the pharmacokinetic reproducibility of mexiletine with the aforementioned prodrugs are also provided.
MEXILETINE AMINO ACID AND PEPTIDE PRODRUGS AND USES THEREOF
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Page/Page column 67; 68, (2011/01/12)
The present invention concerns prodrugs of mexiletine (and mexiletine's active metabolite) with amino acids or peptides and pharmaceutical compositions containing such prodrugs. Methods for providing pain relief, treating arrhythmia, decreasing the advers
