1260071-67-7Relevant academic research and scientific papers
The natural product brartemicin is a high affinity ligand for the carbohydrate-recognition domain of the macrophage receptor mincle
Jacobsen, Kristian M.,Keiding, Ulrik B.,Clement, Lise L.,Schaffert, Eva S.,Rambaruth, Neela D. S.,Johannsen, Mogens,Drickamer, Kurt,Poulsen, Thomas B.
supporting information, p. 647 - 652 (2015/04/27)
We demonstrate that the natural product brartemicin, a newly discovered inhibitor of cancer cell invasion, is a high-affinity ligand of the carbohydrate-recognition domain (CRD) of the C-type lectin mincle. Recent studies have revealed that mincle is a ke
TREHALOSE DERIVATIVES, PREPARATION METHOD AND USES THEREOF
-
Paragraph 0048; 0052, (2014/01/08)
The invention relates to trehalose derivatives with general formula (I), a preparation method and uses thereof, wherein 6,6′-bis(2,3-dimethoxybenzoyl)-α,α-D-trehalose has anti-colon cancer 26-L5 cell invasion activity which is better than that of a natura
Synthesis and structure - Activity relationships studies of brartemicin analogs as anti-invasive agents
Jiang, Yong-Li,Miyanaga, Satoshi,Han, Xiu-Zhen,Tang, Long-Qiang,Igarashi, Yasuhiro,Saiki, Ikuo,Liu, Zhao-Peng
, p. 531 - 537 (2013/10/21)
Brartemicin is a trehalose-based inhibitor of tumor cell invasion produced by the actinomycete of the genus Nonomuraea. In order to find more potent anti-invasive agents and study the structure-activity relationships, a series of 19 brartemicin analogs we
Synthesis and evaluation of trehalose-based compounds as anti-invasive agents
Jiang, Yong-Li,Tang, Long-Qian,Miyanaga, Satoshi,Igarashi, Yasuhiro,Saiki, Ikuo,Liu, Zhao-Peng
experimental part, p. 1089 - 1091 (2011/04/16)
Brartemicin is a trehalose-based inhibitor of tumor cell invasion produced by the actinomycete of the genus Nonomuraea. In order to explore the preliminary structure-activity relationship and obtain more potent inhibitors, a series of brartemicin analogs
