1260145-27-4Relevant articles and documents
Stereoselective approaches to the total synthesis of (6R,4′S, 6′R)-cryptofolione
Sabitha, Gowravaram,Reddy, S. Siva Sankara,Reddy, D. Vasudeva,Bhaskar, Vangala,Yadav, Jhillu S.
experimental part, p. 3453 - 3460 (2010/11/20)
Total syntheses of cryptofolione were accomplished by two different routes via a common intermediate that underwent a cross-metathesis (CM) reaction with a vinyl lactone. The intermediate was prepared by coupling of an acyl anion equivalent with a chiral allyl epoxide synthon, or by Prins cyclization of a trans-cinnamaldehyde with a chiral homoallylic alcohol. Goniothalamin was obtained as a cross-metathesis product of the diacetate and vinyl lactone. Georg Thieme Verlag Stuttgart.