1260152-25-7Relevant academic research and scientific papers
CuI/I2-promoted electrophilic tandem cyclization of 2-ethynylbenzaldehydes with ortho -benzenediamines: Synthesis of iodoisoquinoline-fused benzimidazoles
Ouyang, Huang-Che,Tang, Ri-Yuan,Zhong, Ping,Zhang, Xing-Guo,Li, Jin-Heng
experimental part, p. 223 - 228 (2011/03/18)
An efficient tandem route to the synthesis of iodoisoquinoline-fused benzimidazole derivatives including an iodocyclization strategy has been developed. In the presence of CuI, a variety of 2-ethynylbenzaldehydes underwent the tandem reaction with benzenediamines and iodine to afford the corresponding iodoisoquinoline-fused benzimidazoles in moderate to good yields.
