1260181-13-2Relevant academic research and scientific papers
Identification of a potent janus kinase 3 inhibitor with high selectivity within the janus kinase family
Thoma, Gebhard,Nuninger, Francois,Falchetto, Rocco,Hermes, Erwin,Tavares, Gisele A.,Vangrevelinghe, Eric,Zerwes, Hans-Günter
, p. 284 - 288 (2011/03/22)
We describe a synthetic approach toward the rapid modification of phenyl-indolyl maleimides and the discovery of potent Jak3 inhibitor 1 with high selectivity within the Jak kinase family. We provide a rationale for this unprecedented selectivity based on
