126019-16-7

Upstream product

• 3143-02-0 3-hydroxymethyl-3-methyloxethane 
• 126019-11-2 (1R^*,2S^*,5S^*)-2-acetoxy-5-methyl-3-cyclohexene-1-carboxylic acid 
• 126019-12-3 (1R^*,2S^*,5S^*)-(3-methyl-3-oxetanyl)methyl 2-acetoxy-5-methyl-3-cyclohexenecarboxylate 
• 17616-45-4 1-acetoxy-1,3-pentadiene 
• 1576-86-9 2-pentenal 
• 126019-13-4 (1R^*,2S^*,5S^*)-2-acetoxy-5-methyl-1-(4-methyl-2,6,7-trioxabicyclo<2.2.2>oct-1-yl)-3-cyclohexene 

Downstream Products

• 126019-25-8 (1S^*,2R^*,4S^*,5S^*,6R^*)-9(E)-<2-<(tert-butyldiphenylsilyl)oxy>-1-ethylidene>-1,5-dihydroxy-4-methyl-2-(4-methyl-2,6,7-trioxabicyclo<2.2.2>oct-1-yl)-7-oxabicyclo<4.3.0>nonane 

Relevant academic research and scientific papers

Approaches to avermectin assembly: A concise stereospecific synthesis of the Hexahydrobenzofuran entity

Epoxy ketone 18 was prepared in racemic form via the Diels - Alder reaction of 1-acetoxy-1,3-pentadiene with acrylic acid, subsequent iodolactonization, ortho ester protection, and oxidation. Reaction of 18 with 4-[(tert-butyldiphenylsily) oxy]-2-lithio-1