1260237-41-9Relevant academic research and scientific papers
Synthesis of new cytotoxic E-ring modified camptothecins
Cananzi, Salvatore,Dallavalle, Sabrina,Bargiotti, Alberto,Merlini, Lucio,Artali, Roberto,Beretta, Giovanni Luca
, p. 6489 - 6492 (2010)
In an effort to decrease the toxicity and improve the stability of the E-ring of camptothecin, new analogues with an 'inverted' lactone ring were designed and synthesized. The compounds retained a good cytotoxic activity on human non-small lung cancer cel
