126028-04-4Relevant articles and documents
DECARBOXYLATION OF α-AMINO ACIDS BY PYRUVIC ACID AND ITS DERIVATIVES. EVIDENCE FOR AZOMETHINE YLIDES IN IN VITRO ANALOGUES OF PYRUVOYL ENZYMIC PROCESSES
Grigg, Ronald,Henderson, Deirdre,Hudson, Andrew J.
, p. 2841 - 2844 (2007/10/02)
Reaction of α-amino acids with pyruvic acid, ethyl pyruvate or pyruvamide in hot DMF results in imine formation followed by decarboxylation to generate azomethine ylides stereospecifically.The azomethine ylides undergo stereospecific cycloaddition to N-me