1260422-01-2Relevant academic research and scientific papers
An SN2′ displacement approach to allenyl acetates
Asikainen, Martta,Lewis, William,Blake, Alexander J.,Woodward, Simon
supporting information; experimental part, p. 6454 - 6456 (2011/01/03)
Reaction of cuprates derived from R3MgBr/CuI/LiBr (R3 = n-alkyl) with R1CCCH(O2CR2)2 (R1 = sp2 hybridised substituent, R2 = mainly Me, alkyl, Ph) provides access to allenyl esters R1R 3CCCH(O2CR2) (51-88%). Such species are not accessible via rearrangement of precursor propargylic R1R 3C(O2CR2)CCH.
