126047-75-4 Usage
Uses
Used in Pharmaceutical Industry:
H-GLY-PRO-ARG-PRO-NH2 is used as a constituent of buffer during fluid-phase and bound thrombin inhibition assays. It helps in determining the activity of thrombin, which is essential for the blood coagulation process.
Used in Biomedical Research:
H-GLY-PRO-ARG-PRO-NH2 is used for blocking fibrin polymerization and preventing fibrin clot formation in the presence of α-thrombin. This application is particularly useful in blood obtained from mice, which aids in understanding the mechanisms of blood clotting and developing potential therapeutic agents.
Used in Biochemistry:
H-GLY-PRO-ARG-PRO-NH2 is used during the preparation of human soluble fibrin. It helps in blocking the polymerization of soluble fibrin, which is crucial for studying the structure and function of fibrin and its role in blood clotting and related disorders.
Biochem/physiol Actions
Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).
Check Digit Verification of cas no
The CAS Registry Mumber 126047-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,0,4 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 126047-75:
(8*1)+(7*2)+(6*6)+(5*0)+(4*4)+(3*7)+(2*7)+(1*5)=114
114 % 10 = 4
So 126047-75-4 is a valid CAS Registry Number.
