1260489-73-3Relevant academic research and scientific papers
Facile nucleophilic substitution at the C3a tertiary carbon of the 3a-bromohexahydropyrrolo[2,3-b]indole scaffold
Villanueva-Margalef, Isabel,Thurston, David E.,Zinzalla, Giovanna
experimental part, p. 5294 - 5303 (2011/01/12)
The synthesis of 3a-substituted hexahydropyrrolo[2,3-b]indole derivatives via nucleophilic substitution at the C3a position is reported. Nitrogen-, oxygen-, sulfur-, fluoro- and carbon-based nucleophiles have been employed, using both conventional organic solvents and ionic liquids. The C3a-substituted derivatives were obtained in good to excellent yields. The Royal Society of Chemistry.
