126049-67-0 Usage
Uses
Used in Pharmaceutical Industry:
Cytidine, N-acetyl-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]is used as a potential drug candidate for the development of new pharmaceuticals. The specific modification to the cytidine molecule can have implications in the study and treatment of various diseases and conditions.
Used in Research and Development:
Cytidine, N-acetyl-2',3'-dideoxy-5'-O-[(1,1-dimethylethyl)diphenylsilyl]is used as a research tool for studying the properties and functions of cytidine and its interactions with other molecules and biological processes. This can contribute to a better understanding of RNA and nucleosides, and potentially lead to the discovery of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 126049-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,0,4 and 9 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 126049-67:
(8*1)+(7*2)+(6*6)+(5*0)+(4*4)+(3*9)+(2*6)+(1*7)=120
120 % 10 = 0
So 126049-67-0 is a valid CAS Registry Number.
126049-67-0Relevant academic research and scientific papers
A Highly Stereoselective Synthesis of Anti-HIV 2',3'-Dideoxy- and 2',3'-Didehydro-2',3'-dideoxynucleosides
Beach, J. Warren,Kim, Hea O.,Jeong, Lak S.,Nampalli, Satyanarayana,Islam, Qamrul,et al.
, p. 3887 - 3894 (2007/10/02)
A general total synthesic method for the stereocontrolled synthesis of 2',3'-dideoxy- as well as 2',3'-didehydro-2',3'-dideoxynucleosides is presented.Introduction of an α-phenylselenenyl group at the 2-position of 2,3-dideoxyribosyl acetate directs the glycosyl bond formation to give >/=95percent β-isomer.This 2'-phenylselenenyl nucleoside may be converted to either the 2',3'-dideoxynucleoside by treatment with n-Bu3SnH and Et3B at room temperature or to the unsaturated derivative by treatment with H2O2/cat. pyridine.The application of this method to the syntheses of pyrimidines (ddU, ddT, ddC), 6-substituted purines (ddA, ddI, 6-chloro-ddP, N6-Me-ddA), and 2,6-disubstituted purines (2-F-ddA, 6-chloro-2-amino-ddP) as well as selected 2',3'-didehydro-2',3'-dideoxy derivatives is reported.
