1260587-77-6 Usage
Uses
Used in Pharmaceutical Industry:
(S)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL is used as a key intermediate for the development of pharmaceuticals targeting specific receptors or enzymes in the body. Its unique structure, including the benzylamino group, allows for the creation of drugs with high specificity and potency.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL serves as a versatile building block for the production of various fine chemicals. Its amino and benzylamino groups facilitate the synthesis of complex molecules with potential applications in a range of industries.
Used in Chemical Research:
(S)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL is employed as a valuable tool in chemical research, where its unique structure and properties can be explored for novel reactions and the development of new synthetic methods. (S)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL's chirality also makes it an interesting subject for studying the effects of stereochemistry on reactivity and selectivity in chemical reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1260587-77-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,5,8 and 7 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1260587-77:
(9*1)+(8*2)+(7*6)+(6*0)+(5*5)+(4*8)+(3*7)+(2*7)+(1*7)=166
166 % 10 = 6
So 1260587-77-6 is a valid CAS Registry Number.
1260587-77-6Relevant academic research and scientific papers
Process for N5-formylating tetrahydropteridines
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, (2008/06/13)
Intermediates and a process for the synthesis of 6-monosubstituted tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolic acid. The intermediates are shown in their two enantiomeric forms as follows: STR1 wherein R1 and R2/s
Synthesis of Tetrahydropteridine C6-Stereoisomers, Including N5-Formyl-(6S)-tetrahydrofolic Acid
Bailey, Steven W.,Chandrasekaran, Rama Y.,Ayling, June E.
, p. 4470 - 4477 (2007/10/02)
Chiral N1-protected vicinal diamines derived from amino acids were condensed with 2-amino-6-chloro-5-nitro-4(3H)-pyrimidinone, the nitro group reduced, and the amine deprotected.Oxidative cyclization of the resulting triaminopyrimidinone via quinoid pyrimidine intermediates gave a quinoid dihydropteridine, which was then reduced to a tetrahydropteridine C6-stereoisomer.Thus, 6(R)- and 6(S)-propyltetrahydropterin were stereospecifically synthesized (99 percent enantiomeric purity) in good yield from D- and L-norvaline, respectively.Reductive alkylation of (p-aminobenzoyl)-L-glutamate with a niropyrimidine aldehyde derived from D- or L-serine similarly afforded, after cyclization and reduction, (6R)- or (6S)-tetrahydrofolic acid.The latter was then converted to the natural isomer of leucovorin by regioselective N5-formylation with carbonyl diimidazole / formic acid without loss of enantiomeric purity.
