1260656-25-4Relevant academic research and scientific papers
A copper-catalyzed coupling reaction of vinyl halides and carbazates: Application in the assembly of polysubstituted pyrroles
Zhou, Chengang,Ma, Dawei
supporting information, p. 3085 - 3088 (2014/03/21)
CuI-catalyzed coupling of vinyl halides with carbazates gives N-protected N-alkenylhydrazines, which are condensed with ketones under acidic conditions to give polysubstituted pyrroles. The pyrrole synthesis may go through a similar mechanism with Fischer indole synthesis, which involves a [3,3]-sigmatropic rearrangement and other reactions. The Royal Society of Chemistry.
