1260667-91-1 Usage
General Description
5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde is a chemical compound with the molecular formula C8H8N2O. It is a heterocyclic compound containing a pyrrolopyrazole ring system and an aldehyde functional group. 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde has potential biomedical and pharmaceutical applications due to its ability to act as a building block for the synthesis of various bioactive molecules and pharmaceutical intermediates. It is also used in the development of new drugs and agrochemicals. Additionally, 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-carbaldehyde may have potential industrial applications as a precursor in the synthesis of various fine chemicals. Further research and development may unlock the full potential of this compound in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1260667-91-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,6,6 and 7 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1260667-91:
(9*1)+(8*2)+(7*6)+(6*0)+(5*6)+(4*6)+(3*7)+(2*9)+(1*1)=161
161 % 10 = 1
So 1260667-91-1 is a valid CAS Registry Number.
1260667-91-1Relevant articles and documents
Synthesis of (5,6-dihydro-4h-pyrrolo[1,2-b]pyrazol-3-yl)methanamine
Bai, Zhong-Gang,Qi, Hui,Zhang, Qun-Zheng,Ma, Yu,Pan, Qing,Zhang, Xun-Li
, p. 1923 - 1930 (2017)
This short paper reports the development of a new method for the synthesis of (5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)methanamine. Pyrazole was initially protected with an N-SEM protective group, followed by alkylation at C-5 position with 1-bromo-3-chloropropane. Following SEM deprotection, the intramolecular ring was closed and then a bromine atom (Br) was introduced with N-bromosuccinimide (NBS) by electrophilic aromatic substitution (SEAr), forming 3-bromo-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole. The Br group was subsequently converted into aldehyde group, then into oxime. The final step of hydrogenation resulted in the desired product. The overall yield through the 8-step reaction process was found to be 29.4%. The intermediates and final product were identified by HPLC-MS and 1H NMR. This development provides a novel synthetic route to the formation of 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole skeleton.