1260673-31-1

Basic information

• Product Name: ethyl [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate
• Synonyms: ethyl [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate
• CAS NO: 1260673-31-1
• Molecular Weight: 377.892
• Mol File: 1260673-31-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ethyl [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate(1260673-31-1)
• EPA Substance Registry System: ethyl [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate(1260673-31-1)

Safety Data

• Hazardous Substances Data: 1260673-31-1(Hazardous Substances Data)

Upstream product

• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 1260673-29-7 ethyl (2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)acetate 
• 90534-62-6 2-(2-oxopropyl)cyclohexane-1,3-dione 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 802904-66-1 AZD-1981 
• 1260673-36-6 [3-(4-chlorophenylsulfanyl)-2-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl]acetic acid 
• 1260673-38-8 [3-(4-chlorophenylsulfanyl)-4-(hydroxyimino)-2-methyl-4,5,6,7-tetrahydro-1H-indol-1-yl]acetic acid 
• 646515-19-7 ethyl [4-acetylamino-3-(4-chlorophenylsulfanyl)-2-methyl-1H-indol-1-yl]acetate 
• 1260673-30-0 ethyl [3-(4-chlorophenylsulfanyl)-4-(hydroxyimino)-2-methyl-4,5,6,7-tetrahydro-1H-indol-1-yl]acetate 

Relevant articles and documents

Development of scalable manufacturing routes to AZD1981. Application of the Semmler-Wolff aromatisation for synthesis of the indole-4-amide Core

A safe and efficient synthesis of AZD1981 is described in which the indole 4-amide core is formed by a Semmler-Wolff aromatisation of a cyclohexenone oxime fused to a pyrrole ring. The substrate was obtained via Paal-Knorr pyrrole synthesis, followed by i