1260772-97-1 Usage
Description
1-Piperidinecarboxylic acid, 4-fluoro-3-hydroxy-, 1,1-dimethylethyl ester, commonly known as baclofen, is a medication primarily used to treat spasticity. It is a derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and functions by binding to GABA receptors in the spinal cord, thereby reducing the release of excitatory neurotransmitters and decreasing the number and severity of muscle spasms. This makes it particularly effective in managing spasticity caused by conditions such as multiple sclerosis or spinal cord injuries.
Uses
Used in Pharmaceutical Industry:
Baclofen is used as a muscle relaxant for the treatment of spasticity, a condition characterized by stiff and tight muscles, often resulting from neurological disorders like multiple sclerosis or spinal cord injuries. Its mechanism of action involves binding to GABA receptors, which helps in reducing the frequency and intensity of muscle spasms.
Additionally, baclofen is sometimes administered intrathecally via a pump implant for more direct and controlled delivery to the spinal cord, providing targeted relief for severe spasticity.
Check Digit Verification of cas no
The CAS Registry Mumber 1260772-97-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,0,7,7 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1260772-97:
(9*1)+(8*2)+(7*6)+(6*0)+(5*7)+(4*7)+(3*2)+(2*9)+(1*7)=161
161 % 10 = 1
So 1260772-97-1 is a valid CAS Registry Number.
1260772-97-1Relevant articles and documents
NOVEL HETEROCYCLYL COMPOUNDS
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Page/Page column 26-27, (2011/05/03)
The invention is concerned with novel bicyclic compounds of formula (I), wherein n, m, p, A, L, R1, R2, R3, R4, R5, R6, R7, R7, R8, R9, and R10 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor may be used, for example, in the prevention and/or treatment of inflammatory diseases, particularly peripheral arterial occlusive diseases or atherothrombosis.