126092-07-7

Upstream product

• 2936-70-1 (2R,3S,4S,5S,6R)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 1071917-37-7 C₁₈H₂₄O₆S 
• 316188-14-4 phenyl 4,6-di-O-benzyl-2,3-di-O-isopropylidene-1-thio-α-D-mannopyranoside 
• 126113-70-0 phenyl 4,6-di-O-benzyl-1-thio-α-D-mannopyranoside 
• 126092-08-8 phenyl 2,3-di-O-isopropylidene-1-thio-α-D-mannopyranoside 
• 1350371-76-4 C₇₂H₁₀₆O₁₃ 
• 1350371-75-3 C₅₆H₇₆O₁₂ 
• 1333473-93-0 2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl-(1->1)-2,3-O-isopropylidene-α-D-mannopyranoside 
• 1333473-92-9 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->1)-4,6-di-O-benzyl-3-O-palmitoyl-α-D-mannopyranoside 
• 1333473-91-8 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->1)-4,6-di-O-benzyl-α-D-mannopyranoside 
• 1333473-90-7 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->1)-2,3-O-isopropylidene-4,6-di-O-palmitoyl-α-D-mannopyranoside 
• 1333473-89-4 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->1)-2,3-O-isopropylidene-6-O-palmitoyl-α-D-mannopyranoside 
• 1350363-14-2 C₄₆H₅₄O₁₁ 
• 1333473-88-3 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->1)-2,3-O-isopropylidene-α-D-mannopyranoside 

Relevant academic research and scientific papers

Facile construction of 1,2-cis glucosidic linkage using sequential oxidation-reduction route for synthesis of an ER processing α-glucosidase i substrate

The fluorescence-labeled hexasaccharide (Glcα1-2Glcα1- 3Glcα1-3Manα1-2Manα1-2Manα) was synthesized as a substrate for the processing enzyme α-glucosidase I. To construct the 1,2-cis glucosidic linkages, we employed an α stereoselective coupling using the mannosyl donor by assisted neighboring-group participation, followed by conversion of the stereochemistry of the C-2 hydroxyl group in the mannose residue using sequential oxidation of C-2 hydroxyl group to a 2-keto group and stereoselective reduction of the hydroxyl group to the gluco-configuration to provide the corresponding α-glucoside derivative. Using this strategy, the three consecutive α-glucosidic linkages were easily obtained in a stereoselective manner. Finally, the Dansyl labeled hexasaccharide derivative was used to measure the activity of processing α-glucosidase I.

Synthesis of pyranoid and furanoid glycals from glycosyl sulfoxides by treatment with organolithium reagents

Glycosyl sulfoxides can be conveniently transformed into pyranoid or furanoid glycals by treatment with organolithium reagents. The more likely reaction pathway involves a sulfoxide/metal exchange reaction to generate a glycosyllithium derivative that und