1261079-74-6

Basic information

• Product Name: 2-Chloro-6-methoxypyridine-3-carboxamide
• Synonyms: 2-Chloro-6-methoxypyridine-3-carboxamide
• CAS NO: 1261079-74-6
• Molecular Formula: C₇H₇ClN₂O₂
• Molecular Weight: 186.59568
• Mol File: 1261079-74-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-6-methoxypyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-methoxypyridine-3-carboxamide(1261079-74-6)
• EPA Substance Registry System: 2-Chloro-6-methoxypyridine-3-carboxamide(1261079-74-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1261079-74-6(Hazardous Substances Data)

Upstream product

• 503000-87-1 2-chloro-6-methoxypyridine-3-carboxylic acid 

Relevant articles and documents

From 2,6-dichloronicotinic acid to thiopeptide cores

The scope of 2,6-dichloronicotinic acid as a precursor of thiopeptide polyheterocylic cores has been extensively studied in a cross-coupling-based approach. Differentiation of the two chlorinated positions under SNAr conditions and versatility of the carboxylic acid are key for the preparation of 2,3,6-trisubstituted pyridines with complete regiocontrol. With the present strategy, nine different azole-substituted pyridines were synthesized. Studies towards the selective deprotection of their functionalities resulted in a set of fully orthogonal protecting groups that permits the elongation of all three pyridine substituents. Copyright