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GNF179, also known as GNF-179, is a chemical compound that functions as a potent and selective inhibitor of MAP4K4, a protein kinase implicated in a range of cellular processes. It has demonstrated the ability to effectively suppress the activity of MAP4K4 in both in vitro and in vivo studies, positioning it as a promising candidate for the development of novel therapeutics targeting conditions such as diabetes, cancer, and inflammation. With favorable pharmacokinetic properties and positive outcomes in preclinical studies, GNF179 is a potential drug candidate for further exploration and development. It holds the potential to be a significant tool for elucidating the role of MAP4K4 in physiological and pathological processes, as well as a prospective therapeutic agent for the treatment of various diseases.

1261114-01-5

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1261114-01-5 Usage

Uses

Used in Pharmaceutical Development:
GNF179 is used as a research compound for investigating the role of MAP4K4 in cellular processes and its potential as a therapeutic target for diseases such as diabetes, cancer, and inflammation. Its ability to inhibit MAP4K4 activity makes it a valuable tool in the development of new treatments for these conditions.
Used in Drug Discovery:
GNF179 is utilized as a lead compound in drug discovery efforts, with its selectivity and potency in inhibiting MAP4K4 activity being key factors in identifying potential new drugs for the treatment of related diseases.
Used in Preclinical Studies:
GNF179 is employed as a test subject in preclinical studies to evaluate its safety, efficacy, and pharmacokinetic properties before advancing to clinical trials and potential use in human medicine.
Used in Understanding Cellular Mechanisms:
GNF179 is used as a research tool to explore the mechanisms by which MAP4K4 influences cellular processes, providing insights into the development of targeted therapies and a deeper understanding of the underlying biology of various diseases.
Used in Target Validation:
GNF179 serves as a means to validate MAP4K4 as a therapeutic target, confirming its relevance in the pathophysiology of certain diseases and supporting further investment in research and development of MAP4K4 inhibitors.

Check Digit Verification of cas no

The CAS Registry Mumber 1261114-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,1,1 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1261114-01:
(9*1)+(8*2)+(7*6)+(6*1)+(5*1)+(4*1)+(3*4)+(2*0)+(1*1)=95
95 % 10 = 5
So 1261114-01-5 is a valid CAS Registry Number.

1261114-01-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name GNF179

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1261114-01-5 SDS

1261114-01-5Upstream product

1261114-01-5Downstream Products

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