1261131-68-3

Basic information

• Product Name: 4-(3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropylamino)benzonitrile
• Synonyms: 4-(3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropylamino)benzonitrile
• CAS NO: 1261131-68-3
• Molecular Weight: 321.335
• Mol File: 1261131-68-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropylamino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropylamino)benzonitrile(1261131-68-3)
• EPA Substance Registry System: 4-(3-(1,3-dioxoisoindolin-2-yl)-2-hydroxypropylamino)benzonitrile(1261131-68-3)

Safety Data

• Hazardous Substances Data: 1261131-68-3(Hazardous Substances Data)

Upstream product

• 161596-47-0 (S)-N-glycidylphthalimide 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 1261131-70-7 (S)-4-(5-((1,3-dioxoisoindolin-2-yl)methyl)-2-oxooxazolidin-3-yl)benzonitrile 
• 1027385-05-2 (S)-5-chloro-N-((3-(4-cyanophenyl)-2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide 
• 1082937-34-5 (S)-4-(5-(aminomethyl)-2-oxooxazolidin-3-yl)benzonitrile 
• 1159610-21-5 (S)-5-chloro-N-((3-(4-(5,6-dihydro-4H-1,2,4-oxadiazin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide 

Relevant articles and documents

Design, synthesis and structure - activity relationship of oxazolidinone derivatives containing novel S4 ligand as FXa inhibitors

Abstract A novel series of potent and efficacious factor Xa inhibitors which possesses pyrrole/indole/thiazole moieties as S4 binding element was identified. Compound 7b showed strong human factor Xa inhibitory activity (IC50 = 2.01 nM) and ant