1261174-85-9Relevant academic research and scientific papers
Potent and highly selective DP1 antagonists with 2,3,4,9-tetrahydro-1H- carbazole as pharmacophore
Li, Lianhai,Beaulieu, Christian,Carriere, Marie-Claude,Denis, Danielle,Greig, Gillian,Guay, Daniel,O'Neill, Gary,Zamboni, Robert,Wang, Zhaoyin
, p. 7462 - 7465 (2010)
We discovered that the introduction of a methyl group to the benzylic position of the N-benzyl group in lead compound 1a has a dramatic effect on improving the binding selectivity of this ligand for the prostanoid receptors DP1 (receptor for prostaglandin
