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Ethyl 3-Amino-5-chlorobenzoate is an organic compound that serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is characterized by the presence of an amino group at the 3-position and a chloro substituent at the 5-position on the benzene ring, with an ethyl ester group attached to the carboxylic acid functionality.

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  • 1261269-01-5 Structure
  • Basic information

    1. Product Name: Ethyl 3-AMino-5-chlorobenzoate
    2. Synonyms: Ethyl 3-AMino-5-chlorobenzoate;3-amino-5-chloroBenzoic acid ethyl ester
    3. CAS NO:1261269-01-5
    4. Molecular Formula: C9H10ClNO2
    5. Molecular Weight: 199.6342
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1261269-01-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 340.1±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.262±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 2.44±0.10(Predicted)
    10. CAS DataBase Reference: Ethyl 3-AMino-5-chlorobenzoate(CAS DataBase Reference)
    11. NIST Chemistry Reference: Ethyl 3-AMino-5-chlorobenzoate(1261269-01-5)
    12. EPA Substance Registry System: Ethyl 3-AMino-5-chlorobenzoate(1261269-01-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1261269-01-5(Hazardous Substances Data)

1261269-01-5 Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 3-Amino-5-chlorobenzoate is used as a reactant in the preparation of [2-(2-alkoxyphenyl)cyclopent-1-enyl] substituted (hetero)aromatic carboxylic acids. These compounds exhibit high affinity to the EP1 receptor, which plays a crucial role in various physiological processes, including inflammation, pain, and vascular function. The development of EP1 receptor agonists or antagonists can lead to the discovery of novel therapeutic agents for the treatment of various diseases, such as inflammatory disorders, pain management, and cardiovascular conditions.
Additionally, Ethyl 3-Amino-5-chlorobenzoate can be utilized in the synthesis of other bioactive molecules with potential applications in the pharmaceutical industry. Its unique structural features, such as the presence of an amino and chloro group, make it a versatile building block for the design and development of new drugs with improved pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 1261269-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,2,6 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1261269-01:
(9*1)+(8*2)+(7*6)+(6*1)+(5*2)+(4*6)+(3*9)+(2*0)+(1*1)=135
135 % 10 = 5
So 1261269-01-5 is a valid CAS Registry Number.

1261269-01-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 3-Amino-5-chlorobenzoate

1.2 Other means of identification

Product number -
Other names Ethyl 3-amino-5-chlorobenzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1261269-01-5 SDS

1261269-01-5Upstream product

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