1261284-86-9Relevant academic research and scientific papers
Stereoselective synthesis of hexahydro-3-methyl-1-arylchromeno[3,4-b] pyrrole and its annulated heterocycles as potent antimicrobial agents for human pathogens
Purushothaman,Prasanna,Niranjana,Raghunathan,Nagaraj,Rengasamy
scheme or table, p. 7288 - 7291 (2011/01/12)
Synthesis of a series of novel hexahydrochromenopyrrole analogues has been accomplished through an intramolecular 1,3-dipolar cycloaddition (1,3-DC reaction) of azomethine ylides, generated by the aldehyde induced decarboxylation of secondary amino acids. These compounds were screened for antibacterial and antifungal activities against six human pathogenic bacteria and three human pathogenic fungi and found to have good antimicrobial properties against most of the microorganisms.
