1261287-15-3Relevant academic research and scientific papers
Combination of heme oxygenase-1 inhibition and sigma receptor modulation for anticancer activity
Amata, Emanuele,Calabrese, Loredana,Ciaffaglione, Valeria,D’agata, Velia,D’amico, Agata Grazia,Dichiara, Maria,Grosso, Salvo,Intagliata, Sebastiano,Romeo, Giuseppe,Salerno, Loredana,Sorrenti, Valeria,Vanella, Luca
, (2021)
Cancer is a multifactorial disease that may be tackled by targeting different signaling pathways. Heme oxygenase-1 (HO-1) and sigma receptors (σRs) are both overexpressed in different human cancers, including prostate and brain, contributing to the cancer
Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors
Wi?ckowska, Anna,Bajda, Marek,Guzior, Natalia,Malawska, Barbara
experimental part, p. 5602 - 5611 (2011/02/22)
The study presents synthesis and biological activity of novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties designed as cholinesterases inhibitors. These fragments turned out to determine compounds' selectivi
