1261295-08-2Relevant academic research and scientific papers
Synthesis of new acylsulfamoyl benzoxaboroles as potent inhibitors of HCV NS3 protease
Li, Xianfeng,Zhang, Yong-Kang,Liu, Yang,Zhang, Suoming,Ding, Charles Z.,Zhou, Yasheen,Plattner, Jacob J.,Baker, Stephen J.,Liu, Liang,Bu, Wei,Kazmierski, Wieslaw M.,Wright, Lois L.,Smith, Gary K.,Jarvest, Richard L.,Duan, Maosheng,Ji, Jing-Jing,Cooper, Joel P.,Tallant, Matthew D.,Crosby, Renae M.,Creech, Katrina,Ni, Zhi-Jie,Zou, Wuxin,Wright, Jon
scheme or table, p. 7493 - 7497 (2011/02/24)
HCV NS3/4A serine protease is essential for the replication of the HCV virus and has been a clinically validated target. A series of HCV NS3/4A protease inhibitors containing a novel acylsulfamoyl benzoxaborole moiety at the P1′ region was synthesized and
