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1261301-09-0

O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1261301-09-0 Structure

  • Basic information

    1. Product Name: O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate
    2. Synonyms: O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate
    3. CAS NO:1261301-09-0
    4. Molecular Formula:
    5. Molecular Weight: 407.471
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1261301-09-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate(CAS DataBase Reference)
    10. NIST Chemistry Reference: O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate(1261301-09-0)
    11. EPA Substance Registry System: O-methyl S-phenyl ((R,S)-1-{[(benzyloxy)carbonyl]amino}pent-1-yl)phosphonothiate(1261301-09-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1261301-09-0(Hazardous Substances Data)

1261301-09-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1261301-09-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,3,0 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1261301-09:
(9*1)+(8*2)+(7*6)+(6*1)+(5*3)+(4*0)+(3*1)+(2*0)+(1*9)=100
100 % 10 = 0
So 1261301-09-0 is a valid CAS Registry Number.

1261301-09-0Relevant articles and documents

Synthesis of α-carboxyphosphinopeptides derived from norleucine

Picha, Jan,Budesinsky, Milos,Fiedler, Pavel,Sanda, Miloslav,Jiracek, Jiri

, p. 1265 - 1280 (2011/09/12)

In the present study, we describe in detail the synthesis of a relatively rare class of phosphorus compounds, α-carboxyphosphinopeptides. We prepared several norleucine-derived α-carboxyphosphinic pseudopeptides of the general formula Nle-Ψ[PO(OH)]-Gly. These compounds could have important applications as transition state-mimicking inhibitors for methionine or leucine aminopeptidases or other enzymes. For the preparation of the key α-carboxyphosphinate protected precursors, we investigated, compared and improved two different synthetic methods described in literature: the Arbuzov reaction of a silylated N-protected phosphinic acid with a bromoacetate ester and the nucleophilic addition of a mixed O-methyl S-phenyl N-protected phosphonic acid or a methyl N-protected phosphonochloridate with tert-butyl lithioacetate. We also prepared two N-Fmoc protected synthons, Fmoc-Nle-Ψ[PO(OH)]-Gly-COOH and Fmoc-Nle-Ψ[PO(OAd)]-Gly-COOH, and demonstrated that these precursors are suitable building blocks for the solid-phase synthesis of α-carboxyphosphinopeptides.

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