Cas 1261301-87-4,2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide

1261301-87-4

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Basic information

Product Name: 2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide
Synonyms: 2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide
CAS NO:1261301-87-4
Molecular Formula:
Molecular Weight: 387.893
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide(CAS DataBase Reference)
NIST Chemistry Reference: 2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide(1261301-87-4)
EPA Substance Registry System: 2-(4-chlorophenyl)-4-(S-3-piperidine-amino)-thieno[2,3-d]pyridazine-7-carboxylic acid amide(1261301-87-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1261301-87-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1261301-87-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,3,0 and 1 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1261301-87:
(9*1)+(8*2)+(7*6)+(6*1)+(5*3)+(4*0)+(3*1)+(2*8)+(1*7)=114
114 % 10 = 4
So 1261301-87-4 is a valid CAS Registry Number.

1261301-87-4Upstream product

1261301-89-6 C₂₃H₂₆ClN₅O₃S

1261301-87-4Downstream Products

1261301-87-4Relevant academic research and scientific papers

Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors

Zhao, Lianyun,Zhang, Yingxin,Dai, Chaoyang,Guzi, Timothy,Wiswell, Derek,Seghezzi, Wolfgang,Parry, David,Fischmann, Thierry,Siddiqui, M. Arshad

scheme or table, p. 7216 - 7221 (2011/01/03)

A novel series of CHK1 inhibitors based on thienopyridine template has been designed and synthesized. These inhibitors maintain critical hydrogen bonding with the hinge and conserved water in the ATP binding site. Several compounds show single digit nanomolar CHK1 activities. Compound 70 shows excellent enzymatic activity of 1 nM.

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