1261359-99-2Relevant academic research and scientific papers
Total synthesis, stereochemical assignment, and biological activity of chamuvarinin and structural analogues
Florence, Gordon J.,Morris, Joanne C.,Murray, Ross G.,Vanga, Raghava R.,Osler, Jonathan D.,Smith, Terry K.
, p. 8309 - 8320 (2013/07/27)
A highly stereocontrolled synthesis of (+)-chamuvarinin has been completed in 1.5 % overall yield over 20 steps. The key fragment coupling reactions were the addition of alkyne 8 to aldehyde 7 (under Felkin-Anh control), followed by the two step activatio
