1261491-89-7 Usage
General Description
Olumacostat glasaretil is a chemical compound that acts as a selective and reversible inhibitor of the enzyme acetyl-CoA carboxylase (ACC1). ACC1 is involved in the biosynthesis of fatty acids, and its inhibition may help to reduce excess sebum production in the skin. This makes olumacostat glasaretil a potential treatment for conditions such as acne and oily skin. By targeting the specific enzyme involved in sebum production, olumacostat glasaretil offers a targeted approach to managing these skin conditions, while potentially minimizing side effects associated with broader systemic interventions. Overall, this chemical compound shows promise as a novel therapeutic approach to addressing excess sebum production and its associated dermatological concerns.
Check Digit Verification of cas no
The CAS Registry Mumber 1261491-89-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,1,4,9 and 1 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1261491-89:
(9*1)+(8*2)+(7*6)+(6*1)+(5*4)+(4*9)+(3*1)+(2*8)+(1*9)=157
157 % 10 = 7
So 1261491-89-7 is a valid CAS Registry Number.
1261491-89-7Relevant articles and documents
DERMATOLOGICAL FORMULATIONS OF 2-(2-ETHOXY-2-OXOETHYL)(METHYL)AMINO-2-OXOETHYL 5-(TETRADECYLOXY)FURAN-2-CARBOXYLATE
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Paragraph 26; 32-33, (2018/02/28)
Disclosed herein are dermatological formulations comprising low-impurity TOFA prodrug 2-(2-ethoxy-2-oxoethyl)(methyl)amino-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate represented by Formula (la) and pharmaceutical use thereof.
SYNTHETIC PROCESS FOR PREPARING 2-((2-ETHOXY-2-OXOETHYL)(METHYL)AMINO)-2-OXOETHYL 5-TETRADECYLOXY)FURAN-2-CARBOXYLATE
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Paragraph 0047; 0048, (2016/09/08)
Disclosed herein are processes for forming 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate:
