1261555-87-6Relevant articles and documents
An atom-economic synthesis of nitrogen heterocycles from alkynes
Trost, Barry M.,Lumb, Jean-Philip,Azzarelli, Joseph M.
supporting information; experimental part, p. 740 - 743 (2011/04/15)
A robust route to 2,4-disubstituted pyrrole heterocycles relying upon a cascade reaction is reported. The reaction benefits from operational simplicity: it is air and moisture tolerant and is performed at ambient temperature. Control over the reaction conditions provides ready access to isopyrroles, 2,3,4-trisubstituted pyrroles, and 3-substituted pyrollidin-2-ones.
