1261629-31-5

Basic information

• Product Name: 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE
• Synonyms: 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE
• CAS NO: 1261629-31-5
• Molecular Weight: 164.542
• EINECS: -0
• Mol File: 1261629-31-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE(1261629-31-5)
• EPA Substance Registry System: 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE(1261629-31-5)

Safety Data

• Hazardous Substances Data: 1261629-31-5(Hazardous Substances Data)

Usage

General Description

2-Chloro-4-(difluoromethyl)pyrimidine is a chemical compound with the molecular formula C5H2ClF2N2. It is a pyrimidine derivative with a chlorine atom at the 2-position and a difluoromethyl group at the 4-position. 2-CHLORO-4-(DIFLUOROMETHYL)PYRIMIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. It is also used in the production of herbicides, fungicides, and insecticides. 2-Chloro-4-(difluoromethyl)pyrimidine is a highly reactive and versatile building block in organic synthesis, making it a valuable compound in the chemical industry. Additionally, it is important to handle this compound with caution, as it is toxic and may pose health risks if not handled properly.

Upstream product

• 1722-12-9 2-chloropyrimidine 
• 885702-34-1 2-chloro-4-bromopyrimidine 
• 1511-62-2 bromodifluoromethane 
• 401-67-2 2,2-difluoroacetic anhydride 
• 109-92-2 ethyl vinyl ether 
• 57-13-6 urea 

Downstream Products

• 621-38-5 3-bromoacetanilide 

Relevant articles and documents

The direct C-H difluoromethylation of heteroarenes based on the photolysis of hypervalent iodine(III) reagents that contain difluoroacetoxy ligands

In this letter, an efficient method for the photolytic generation of difluoromethyl radicals from [bis(difluoroacetoxy)iodo]benzene reagents is described. The present approach enables the introduction of difluoromethyl groups into various heteroarenes und

THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein ring R1, R2, R3, R4, ring B, and the subscript r are as defi

THIAZOLE-SUBSTITUTED AMINOHETEROARYLS AS SPLEEN TYROSINE KINASE INHIBITORS

The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, Y1, Y2, Y3, Y4, and R4 are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).