126186-87-6Relevant articles and documents
Asymmetric hydrogenolysis of racemic tertiary alcohols, 3-substituted 3-hydroxyisoindolin-1-ones
Chen, Mu-Wang,Chen, Qing-An,Duan, Ying,Ye, Zhi-Shi,Zhou, Yong-Gui
, p. 1698 - 1700 (2012)
Asymmetric hydrogenolysis of racemic tertiary alcohols, 3-substituted 3-hydroxyisoindolin-1-ones, was developed using chiral phosphoric acid as catalyst and a Hantzsch ester as the hydrogen source with up to 95% ee. The reaction process of this asymmetric