126190-76-9Relevant academic research and scientific papers
Synthesis, spectroscopic and cytotoxic studies of biologically active new Schiff bases derived from p-nitrobenzaldehyde
Iqbal, Amjid,Siddiqui, Hamid Latif,Ashraf, Chaudhary Muhammad,Bukhari, Mujahid Hussain,Akram, Chaudhary Muhammad
, p. 1070 - 1072 (2007)
Thirteen new Schiff bases derived from p-nitrobenzaldehyde were synthesized by condensation with the appropriate amines. An unusual reduction of the p-nitrobenzaldehyde to the corresponding alcohol was also observed in one of the reactions. The structures of the compounds were identified using spectroscopic techniques. Cytotoxicity for the titled compounds was studied against Brine Shrimp, used as the test animal.
One-pot sequence synthesis of azetidin-2-one using diethyl chlorophosphate
Zarei, Maaroof
experimental part, p. 118 - 120 (2012/05/04)
A simple and convenient synthesis of 2-azetidinone derivatives from the reaction of a pre-mixture of amines and aldehydes with carboxylic acids in the presence of diethyl chlorophosphate by [2+2] cycloaddition reaction is described. Separation and purification of imines as intermediates were not required. The methodology is convenient and good to excellent yields of products were obtained with simple purification.
