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1262005-03-7

C25H27N3O4S is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1262005-03-7 Structure

  • Basic information

    1. Product Name: C25H27N3O4S
    2. Synonyms: C25H27N3O4S
    3. CAS NO:1262005-03-7
    4. Molecular Formula:
    5. Molecular Weight: 465.573
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1262005-03-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C25H27N3O4S(CAS DataBase Reference)
    10. NIST Chemistry Reference: C25H27N3O4S(1262005-03-7)
    11. EPA Substance Registry System: C25H27N3O4S(1262005-03-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1262005-03-7(Hazardous Substances Data)

1262005-03-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1262005-03-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,0,0 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1262005-03:
(9*1)+(8*2)+(7*6)+(6*2)+(5*0)+(4*0)+(3*5)+(2*0)+(1*3)=97
97 % 10 = 7
So 1262005-03-7 is a valid CAS Registry Number.

1262005-03-7Upstream product

1262005-03-7Relevant articles and documents

Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents

Bekhit, Adnan A.,Fahmy, Hesham T.Y.,Rostom, Sherif A.F.,Bekhit, Alaa El-Din A.

, p. 6027 - 6038 (2010)

The synthesis of a novel series of 4-thiazolylpyrazolyl derivatives is described in the present report. All the newly synthesized compounds were examined for their anti-inflammatory activity using cotton pellet-induced granuloma and carrageenan-induced rat paw edema bioassays. Their inhibitory activities of cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2), ulcerogenic effect and acute toxicity were also determined. Furthermore, all compounds were evaluated for their in vitro antimicrobial activity against Escherichia coli, Staphylococcus aureus and Candida albicans. A docking pose for compounds 8b, 10a and 10b separately in the active site of the human COX-2 enzyme and DNA-gyrase B was also obtained. The results revealed that compounds 8b, 10a and 10b exhibited good anti-inflammatory activity with no or minimal ulcerogenic effect and good safety margin. Compounds 10a and 10b were found to be the most potent anti-inflammatory agents in the present study. Meanwhile, 10a and 10b displayed higher selective inhibitory activity towards COX-2 compared to indomethacin. Moreover, compounds 10a and 10b exhibited promising antibacterial against both E. coli and S. aureus. Docking studies for 8b, 10a and 10b with COX-2 (PDB ID: 1CX2) and DNA-gyrase B (PDB ID: 1EI1) showed good binding profile.

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