1262036-49-6 Usage
General Description
N-[3-[(4aS,7aS)-2-Amino-5,7-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(4aH)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride is a chemical compound with potential pharmacological properties. It is a hydrochloride salt of a derivative of pyridinecarboxamide, and it contains an amino group and fluorine atoms attached to a furothiazinylphenyl moiety. N-[3-[(4aS,7aS)-2-Amino-5,7-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(4aH)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride may have potential applications in the development of pharmaceutical drugs, specifically in the field of medicinal chemistry and drug discovery. Further research and studies are needed to fully understand and determine the specific uses and effects of this chemical entity.
Check Digit Verification of cas no
The CAS Registry Mumber 1262036-49-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,0,3 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1262036-49:
(9*1)+(8*2)+(7*6)+(6*2)+(5*0)+(4*3)+(3*6)+(2*4)+(1*9)=126
126 % 10 = 6
So 1262036-49-6 is a valid CAS Registry Number.
1262036-49-6Relevant articles and documents
Synthesis of BACE Inhibitor LY2886721. Part II. Isoxazolidines as Precursors to Chiral Aminothiazines, Selective Peptide Coupling, and a Controlled Reactive Crystallization
Hansen, Marvin M.,Jarmer, Daniel J.,Arslantas, Enver,DeBaillie, Amy C.,Frederick, Andrea L.,Harding, Molly,Hoard, David W.,Hollister, Adrienne,Huber, Dominique,Kolis, Stanley P.,Kuehne-Willmore, Jennifer E.,Kull, Thomas,Laurila, Michael E.,Linder, Ryan J.,Martin, Thomas J.,Martinelli, Joseph R.,McCulley, Michael J.,Richey, Rachel N.,Starkey, Derek R.,Ward, Jeffrey A.,Zaborenko, Nikolay,Zweifel, Theo
, p. 1214 - 1230 (2015)
An efficient synthesis of LY2886721 (1) in five steps and 46% overall yield from the chiral nitrone cycloadduct 2 is presented. Minimizing formation of a des-fluoro impurity during hydrogenolysis to cleave the isoxazolidine ring and remove the benzyl chir
