1262044-52-9

Basic information

• Product Name: 1,2-dimethyl-3-(phenylethynyl)benzene
• Synonyms: 1,2-dimethyl-3-(phenylethynyl)benzene
• CAS NO: 1262044-52-9
• Molecular Weight: 206.287
• Mol File: 1262044-52-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-dimethyl-3-(phenylethynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dimethyl-3-(phenylethynyl)benzene(1262044-52-9)
• EPA Substance Registry System: 1,2-dimethyl-3-(phenylethynyl)benzene(1262044-52-9)

Safety Data

• Hazardous Substances Data: 1262044-52-9(Hazardous Substances Data)

Upstream product

• 608-23-1 3-chloro-o-xylene 
• 637-44-5 phenylpropyolic acid 
• 576-23-8 2,3-dimethylbromobenzene 
• 536-74-3 phenylacetylene 
• 31599-60-7 1-iodo-2,3-dimethylbenzene 

Relevant articles and documents

Thermoregulated aqueous biphasic catalysis of sonogashira reactions

A water-based thermoregulated system for Pd-catalyzed Sonogashira reactions is presented, which allows for not only a highly efficient homogeneous catalytic reaction, but also an easy separation/recovery of the catalyst. The novel catalytic system exhibits high efficiency and excellent reusability. In addition, the Sonogashira reactions are performed with Pd(OAc)2 without a copper co-catalyst.

Palladacycle-catalyzed decarboxylative coupling of alkynyl carboxylic acids with aryl chlorides under air

A highly efficient and practical protocol for palladacycle-catalyzed decarboxylative coupling of alkynyl carboxylic acids with aryl chlorides was developed. The reaction could proceed smoothly in air within 3 h under optimized reaction conditions (1 mol % of palladacycle, 4 mol % of Xphos, 2.0 equiv of K2CO3 in xylene/H2O), affording the corresponding internal alkynes in mostly good to excellent yields. Remarkably, this result represents the first successful examples of this type of decarboxylative cross-coupling using electron-poor, electron-neutral and even inactive sterically hindered electron-rich aryl chlorides as the starting materials.