1262046-23-0

Basic information

• Product Name: dicyclohexyl [(2',6'-diisopropyl-3,6-dimethoxy-1-1'-biphenyl)2-yl]phosphine
• Synonyms: dicyclohexyl [(2',6'-diisopropyl-3,6-dimethoxy-1-1'-biphenyl)2-yl]phosphine
• CAS NO: 1262046-23-0
• Molecular Weight: 494.698
• Mol File: 1262046-23-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dicyclohexyl [(2',6'-diisopropyl-3,6-dimethoxy-1-1'-biphenyl)2-yl]phosphine(CAS DataBase Reference)
• NIST Chemistry Reference: dicyclohexyl [(2',6'-diisopropyl-3,6-dimethoxy-1-1'-biphenyl)2-yl]phosphine(1262046-23-0)
• EPA Substance Registry System: dicyclohexyl [(2',6'-diisopropyl-3,6-dimethoxy-1-1'-biphenyl)2-yl]phosphine(1262046-23-0)

Safety Data

• Hazardous Substances Data: 1262046-23-0(Hazardous Substances Data)

Upstream product

• 16523-54-9 chlorodicyclohexylphosphane 
• 57190-17-7 2-bromo-1,3-diisopropylbenzene 

Relevant articles and documents

Mechanistic Insight Leads to a Ligand Which Facilitates the Palladium-Catalyzed Formation of 2-(Hetero)Arylaminooxazoles and 4-(Hetero)Arylaminothiazoles

By using mechanistic insight, a new ligand (EPhos) for the palladium-catalyzed C?N cross-coupling between primary amines and aryl halides has been developed. Employing an isopropoxy group at the C3-position favors the C-bound isomer of the ligand-supported palladium(II) complexes and leads to significantly improved reactivity. The use of a catalyst system based on EPhos with NaOPh as a mild homogeneous base proved to be very effective in the formation of 4-arylaminothiazoles and highly functionalized 2-arylaminooxazoles. Previously, these were not readily accessible using palladium catalysis.