1262053-60-0

Basic information

• Product Name: OxyMetazoline-d4
• Synonyms: OxyMetazoline-d4;2-(4-tert-Butyl-2,6-diMethyl-3-hydroxybenzyl)-2-iMidazoline-d4;3-[(4,5-Dihydro-1H-iMidazol-2-yl)Methyl]-6-(1,1-diMethylethyl)-2,4-diMethylphenol-d4;6-tert-Butyl-3-(2-iMidazolin-2-ylMethyl)-2,4-diMethylphenol-d4;Hazol-d4;Navasin-d4;Navisin-d4;Nezeril-d4
• CAS NO: 1262053-60-0
• Molecular Formula: C₁₆H₂₄N₂O
• Molecular Weight: 296.8355
• Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1262053-60-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: OxyMetazoline-d4(CAS DataBase Reference)
• NIST Chemistry Reference: OxyMetazoline-d4(1262053-60-0)
• EPA Substance Registry System: OxyMetazoline-d4(1262053-60-0)

Safety Data

• Hazardous Substances Data: 1262053-60-0(Hazardous Substances Data)

Usage

Uses

The labelled analogue of a vasoconstrictor, OxyMetazoline-d4 can be used as a nasal decongestant.

Upstream product

• 37164-19-5 ethylene-d4-diamine 
• 55699-10-0 2-(4-tert-butyl-3-hydroxy-2,6-dimethylphenyl)acetonitrile 

Relevant articles and documents

Synthesis of [2H4]oxymetazoline and [ 14C]oxymetazoline

An efficient synthesis of [2H4] and [ 14C]oxymetazoline has been developed. Both compounds follow the same synthetic route with the introduction of the label occurring at different synthetic steps. The synthesis of [2H4]oxymetazoline from [2H4]ethylene diamine was achieved in one step with a 40% yield. The synthesis of [14C]oxymetazoline from potassium [ 14C]cyanide was achieved in two steps with an overall radiochemical yield of 67%. Copyright