1262055-66-2Relevant academic research and scientific papers
Ruthenium porphyrins-catalyzed atom-efficient amination of C-H bonds by arylazides
Intrieri, Daniela,Caselli, Alessandro,Ragaini, Fabio,Cenini, Sergio,Gallo, Emma
experimental part, p. 732 - 740 (2011/11/14)
Benzylic amines are synthesized in yield up to 90% by the Ru(TPP)CO-catalyzed amination of both exocyclic and endocyclic benzylic C-H bonds. The choice of arylazides as nitrogen sources confers to the methodology a good sustainability due to the formation of molecular nitrogen as the only stoichiometric by-product. A preliminary mechanistic investigation evidenced a critical role of the hydrocarbon concentration to drive the chemoselectivity of the reaction.
